A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the pathway a therapeutic target. The similarity between t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Lin, Tony Eight, HuangFu, Wei-Chun, Chao, Min-Wu, Sung, Tzu-Ying, Chang, Chao-Di, Chen, Yi-Ying, Hsieh, Jui-Hua, Tu, Huang-Ju, Huang, Han-Li, Pan, Shiow-Lin, Hsu, Kai-Cheng
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288363/
https://ncbi.nlm.nih.gov/pubmed/30564118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01379
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