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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

BACKGROUND: Despite the fact that histone deacetylase (HDAC) inhibitors have been tested to treat various cardiovascular diseases, the effects of selective HDAC6 inhibitor ACY1215 on infarct size during cardiac ischemia-reperfusion (IR) injury still remain unknown. In the present study we aimed to i...

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Détails bibliographiques
Publié dans:BMC Pharmacol Toxicol
Auteurs principaux: Lin, Chao-Feng, Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Huang, Han-Li, Pan, Shiow-Lin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077123/
https://ncbi.nlm.nih.gov/pubmed/32178737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-0400-0
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