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A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions
The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the pathway a therapeutic target. The similarity between t...
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| Publicat a: | Front Pharmacol |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6288363/ https://ncbi.nlm.nih.gov/pubmed/30564118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01379 |
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