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A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
The immune system works in conjunction with inflammation. Excessive inflammation underlies various human diseases, such as asthma, diabetes and heart disease. Previous studies found that 5-lipoxygenase (5-LOX) plays a crucial role in metabolizing arachidonic acid into inflammatory mediators and is a...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7324578/ https://ncbi.nlm.nih.gov/pubmed/32601404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67420-9 |
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