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Design of cyclic and D-amino acids containing peptidomimetics for inhibition of protein-protein interactions of HER2-HER3
HER2 receptors are surface proteins belonging to the epidermal growth factor family of receptors (EGFR). Their numbers are elevated in breast, lung, and ovarian cancers. HER2-positive cancers are aggressive, higher mortality rate and have a poor prognosis. We have designed peptidomimetics that bind...
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| Publicado en: | J Pept Sci |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6284401/ https://ncbi.nlm.nih.gov/pubmed/29436155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.3066 |
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