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A peptidomimetic with a chiral switch is an inhibitor of epidermal growth factor receptor heterodimerization
Among different types of EGFR dimers, EGFR-HER2 and HER2-HER3 are well known in different types of cancers. Targeting dimerization of EGFR will have a significant impact on cancer therapies. A symmetric peptidomimetic was designed to inhibit the protein-protein interaction of EGFR. The peptidomimeti...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650337/ https://ncbi.nlm.nih.gov/pubmed/29088782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19013 |
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