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A grafted peptidomimetic for EGFR heterodimerization inhibition: implications in NSCLC models.

Among the lung cancers, approximately 85% are histologically classified as non-small-cell lung cancer (NSCLC), a leading cause of cancer deaths worldwide. Epidermal growth factor receptors (EGFRs) are known to play a crucial role in lung cancer. HER2 overexpression is detected by immunohistochemistr...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Singh, Sitanshu S., Mattheolabakis, George, Gu, Xin, Withers, Sita, Dahal, Achyut, Jois, Seetharama
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044046/
https://ncbi.nlm.nih.gov/pubmed/33667849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2021.113312
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