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Design of a doxorubicin-peptidomimetic conjugate that targets HER2-positive cancer cells
Doxorubicin (DOX) belongs to the anthracycline class of drugs that are used in the treatment of various cancers. It has limited cystostatic effects in therapeutic doses, but higher doses can cause cardiotoxicity. In the current approach, we conjugated a peptidomimetic (Arg-aminonaphthylpropionic aci...
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| Izdano u: | Eur J Med Chem |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148673/ https://ncbi.nlm.nih.gov/pubmed/27769032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.10.015 |
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