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Design of a doxorubicin-peptidomimetic conjugate that targets HER2-positive cancer cells
Doxorubicin (DOX) belongs to the anthracycline class of drugs that are used in the treatment of various cancers. It has limited cystostatic effects in therapeutic doses, but higher doses can cause cardiotoxicity. In the current approach, we conjugated a peptidomimetic (Arg-aminonaphthylpropionic aci...
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| Veröffentlicht in: | Eur J Med Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148673/ https://ncbi.nlm.nih.gov/pubmed/27769032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.10.015 |
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