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Design of cyclic and D-amino acids containing peptidomimetics for inhibition of protein-protein interactions of HER2-HER3

HER2 receptors are surface proteins belonging to the epidermal growth factor family of receptors (EGFR). Their numbers are elevated in breast, lung, and ovarian cancers. HER2-positive cancers are aggressive, higher mortality rate and have a poor prognosis. We have designed peptidomimetics that bind...

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Bibliografski detalji
Izdano u:J Pept Sci
Glavni autori: Pallerla, Sandeep, Naik, Himgauri, Singh, Sitanshu, Gauthier, Ted, Sable, Rushikesh, Jois, Seetharama D.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284401/
https://ncbi.nlm.nih.gov/pubmed/29436155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.3066
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