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Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein–Protein Interaction

The interaction between the cell–cell adhesion proteins CD2 and CD58 plays a crucial role in lymphocyte recruitment to inflammatory sites, and inhibitors of this interaction have potential as immunomodulatory drugs in autoimmune diseases. Peptides from the CD2 adhesion domain were designed to inhibi...

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書目詳細資料
發表在:ACS Chem Biol
Main Authors: Sable, Rushikesh, Durek, Thomas, Taneja, Veena, Craik, David J., Pallerla, Sandeep, Gauthier, Ted, Jois, Seetharama
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091667/
https://ncbi.nlm.nih.gov/pubmed/27337048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00486
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