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Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors

Blocking protein-protein interactions (PPI) using small molecules or peptides modulates biochemical pathways and has therapeutic significance. PPI inhibition for designing drug-like molecules is a new area that has been explored extensively during the last decade. Considering the number of available...

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Vydáno v:Molecules
Hlavní autoři: Sable, Rushikesh, Jois, Seetharama
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272567/
https://ncbi.nlm.nih.gov/pubmed/26111183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200611569
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