Synergistic cross‐talk of hedgehog and interleukin‐6 signaling drives growth of basal cell carcinoma

Persistent activation of hedgehog (HH)/GLI signaling accounts for the development of basal cell carcinoma (BCC), a very frequent nonmelanoma skin cancer with rising incidence. Targeting HH/GLI signaling by approved pathway inhibitors can provide significant therapeutic benefit to BCC patients. Howev...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Sternberg, Christina, Gruber, Wolfgang, Eberl, Markus, Tesanovic, Suzana, Stadler, Manuela, Elmer, Dominik P., Schlederer, Michaela, Grund, Sandra, Roos, Simone, Wolff, Florian, Kaur, Supreet, Mangelberger, Doris, Lehrach, Hans, Hache, Hendrik, Wierling, Christoph, Laimer, Josef, Lackner, Peter, Wiederstein, Markus, Kasper, Maria, Risch, Angela, Petzelbauer, Peter, Moriggl, Richard, Kenner, Lukas, Aberger, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Molecular Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282712/
https://ncbi.nlm.nih.gov/pubmed/29987839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31724
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