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Cooperative Hedgehog-EGFR signaling

It has been known for many years that cooperative interactions between oncogenes (e.g. RAS, MYC, BCL2) can fuel cancer growth (1-5), but the restricted druggability of many of those interacting cancer genes has hampered translation of combined targeting to medical cancer therapy. The identification...

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Main Authors: Mangelberger, Doris, Kern, Daniela, Loipetzberger, Andrea, Eberl, Markus, Aberger, Fritz
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284771/
https://ncbi.nlm.nih.gov/pubmed/22201734
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