Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway

Persistent activation of the Hedgehog (HH)/GLI signaling pathway has been implicated in the development of a number of human cancers. The GLI zinc finger transcription factors act at the end of the HH signaling cascade to control gene expression, and recent studies have shown that the activity of GL...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Schnidar, Harald, Eberl, Markus, Klingler, Stefan, Mangelberger, Doris, Kasper, Maria, Hauser-Kronberger, Cornelia, Regl, Gerhard, Kroismayr, Renate, Moriggl, Richard, Sibilia, Maria, Aberger, Fritz
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035872/
https://ncbi.nlm.nih.gov/pubmed/19190345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2331
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi