Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway

Persistent activation of the Hedgehog (HH)/GLI signaling pathway has been implicated in the development of a number of human cancers. The GLI zinc finger transcription factors act at the end of the HH signaling cascade to control gene expression, and recent studies have shown that the activity of GL...

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Hauptverfasser: Schnidar, Harald, Eberl, Markus, Klingler, Stefan, Mangelberger, Doris, Kasper, Maria, Hauser-Kronberger, Cornelia, Regl, Gerhard, Kroismayr, Renate, Moriggl, Richard, Sibilia, Maria, Aberger, Fritz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035872/
https://ncbi.nlm.nih.gov/pubmed/19190345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2331
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