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Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy

The Hedgehog/Glioma-associated oncogene homolog (HH/GLI) signaling pathway regulates self-renewal of rare and highly malignant cancer stem cells (CSC), which have been shown to account for the initiation and maintenance of tumor growth as well as for drug resistance, metastatic spread and relapse. E...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Peer, Elisabeth, Tesanovic, Suzana, Aberger, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520835/
https://ncbi.nlm.nih.gov/pubmed/30991683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040538
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