Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking

P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously, we found that...

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Bibliografische gegevens
Gepubliceerd in:J Cereb Blood Flow Metab
Hoofdauteurs: Tome, Margaret E, Jarvis, Chelsea K, Schaefer, Charles P, Jacobs, Leigh M, Herndon, Joseph M, Hunn, Kristen C, Arkwright, Nathan B, Kellohen, Kathryn L, Mierau, Peyton C, Davis, Thomas P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2018
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282220/
https://ncbi.nlm.nih.gov/pubmed/30346224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18803623
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