Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking

P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously, we found that...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Tome, Margaret E, Jarvis, Chelsea K, Schaefer, Charles P, Jacobs, Leigh M, Herndon, Joseph M, Hunn, Kristen C, Arkwright, Nathan B, Kellohen, Kathryn L, Mierau, Peyton C, Davis, Thomas P
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282220/
https://ncbi.nlm.nih.gov/pubmed/30346224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18803623
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