Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking

P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously, we found that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cereb Blood Flow Metab
Prif Awduron: Tome, Margaret E, Jarvis, Chelsea K, Schaefer, Charles P, Jacobs, Leigh M, Herndon, Joseph M, Hunn, Kristen C, Arkwright, Nathan B, Kellohen, Kathryn L, Mierau, Peyton C, Davis, Thomas P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282220/
https://ncbi.nlm.nih.gov/pubmed/30346224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18803623
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