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Olanzapine metabolism and the significance of the UGT1A4(48V) and UGT2B10(67Y) variants
Olanzapine (OLZ) is an antipsychotic used in the treatment of schizophrenia, bipolar disorder, and treatment-resistant depression. Glucuronidation via the UDP-glucuronosyltransferase (UGT) family of enzymes is the major mode of OLZ metabolism and polymorphisms in these enzymes could contribute to in...
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| Publicado no: | Pharmacogenet Genomics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281394/ https://ncbi.nlm.nih.gov/pubmed/21750471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328348c76b |
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