Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have the potential to conjugate two asymmetrical g...

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Detalles Bibliográficos
Publicado en:Front Chem
Main Authors: Alapour, Saba, Sharma, Anamika, de la Torre, Beatriz G., Ramjugernath, Deresh, Koorbanally, Neil A., Albericio, Fernando
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Chemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279949/
https://ncbi.nlm.nih.gov/pubmed/30547028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00589
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