Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have the potential to conjugate two asymmetrical g...

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Bibliographische Detailangaben
Veröffentlicht in:Front Chem
Hauptverfasser: Alapour, Saba, Sharma, Anamika, de la Torre, Beatriz G., Ramjugernath, Deresh, Koorbanally, Neil A., Albericio, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279949/
https://ncbi.nlm.nih.gov/pubmed/30547028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00589
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