Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have the potential to conjugate two asymmetrical g...

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Vydáno v:Front Chem
Hlavní autoři: Alapour, Saba, Sharma, Anamika, de la Torre, Beatriz G., Ramjugernath, Deresh, Koorbanally, Neil A., Albericio, Fernando
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279949/
https://ncbi.nlm.nih.gov/pubmed/30547028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00589
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