Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have the potential to conjugate two asymmetrical g...

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Bibliographic Details
Published in:Front Chem
Main Authors: Alapour, Saba, Sharma, Anamika, de la Torre, Beatriz G., Ramjugernath, Deresh, Koorbanally, Neil A., Albericio, Fernando
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279949/
https://ncbi.nlm.nih.gov/pubmed/30547028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00589
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