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Methods for Improving Aptamer Binding Affinity
Aptamers are single stranded oligonucleotides that bind a wide range of biological targets. Although aptamers can be isolated from pools of random sequence oligonucleotides using affinity-based selection, aptamers with high affinities are not always obtained. Therefore, further refinement of aptamer...
Guardat en:
| Publicat a: | Molecules |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6273865/ https://ncbi.nlm.nih.gov/pubmed/27043498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040421 |
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