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Methods for Improving Aptamer Binding Affinity

Aptamers are single stranded oligonucleotides that bind a wide range of biological targets. Although aptamers can be isolated from pools of random sequence oligonucleotides using affinity-based selection, aptamers with high affinities are not always obtained. Therefore, further refinement of aptamer...

詳細記述

保存先:
書誌詳細
出版年:Molecules
主要な著者: Hasegawa, Hijiri, Savory, Nasa, Abe, Koichi, Ikebukuro, Kazunori
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273865/
https://ncbi.nlm.nih.gov/pubmed/27043498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040421
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