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Screening of DNA Aptamer Against Mouse Prion Protein by Competitive Selection

Prion disease is a neurodegenerative disorder, in which the normal prion protein (PrP) changes structurally into an abnormal form and accumulates in the brain. There is a great demand for the development of a viable approach to diagnosis and therapy. Not only has the ligand against PrP been used for...

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Autori principali: Ogasawara, Daisuke, Hasegawa, Hijiri, Kaneko, Kiyotoshi, Sode, Koji, Ikebukuro, Kazunori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634539/
https://ncbi.nlm.nih.gov/pubmed/19164908
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