Synthesis, (18)F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography

Phosphodiesterase 2A (PDE2A) is highly and specifically expressed in particular brain regions that are affected by neurological disorders and in certain tumors. Development of a specific PDE2A radioligand would enable molecular imaging of the PDE2A protein via positron emission tomography (PET). Her...

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Gepubliceerd in:Molecules
Hoofdauteurs: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Egerland, Ute, Kranz, Mathias, Scheunemann, Matthias, Höfgen, Norbert, Steinbach, Jörg, Brust, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272448/
https://ncbi.nlm.nih.gov/pubmed/26016549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20069591
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