Development of (18)F-Labeled Radiotracers for PET Imaging of the Adenosine A(2A) Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation

The adenosine A(2A) receptor (A(2A)R) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during the A(2A)R-tailored therapy, we designed a libr...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Lai, Thu Hang, Schröder, Susann, Toussaint, Magali, Dukić-Stefanović, Sladjana, Kranz, Mathias, Ludwig, Friedrich-Alexander, Fischer, Steffen, Steinbach, Jörg, Deuther-Conrad, Winnie, Brust, Peter, Moldovan, Rareş-Petru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956753/
https://ncbi.nlm.nih.gov/pubmed/33669003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052285
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