Improved in vivo PET imaging of the adenosine A(2A) receptor in the brain using [(18)F]FLUDA, a deuterated radiotracer with high metabolic stability

PURPOSE: The adenosine A(2A) receptor has emerged as a therapeutic target for multiple diseases, and thus the non-invasive imaging of the expression or occupancy of the A(2A) receptor has potential to contribute to diagnosis and drug development. We aimed at the development of a metabolically stable...

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Bibliografski detalji
Izdano u:Eur J Nucl Med Mol Imaging
Glavni autori: Lai, Thu Hang, Toussaint, Magali, Teodoro, Rodrigo, Dukić-Stefanović, Sladjana, Gündel, Daniel, Ludwig, Friedrich-Alexander, Wenzel, Barbara, Schröder, Susann, Sattler, Bernhard, Moldovan, Rareş-Petru, Falkenburger, Björn H., Sabri, Osama, Deuther-Conrad, Winnie, Brust, Peter
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2021
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263428/
https://ncbi.nlm.nih.gov/pubmed/33532910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05164-4
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