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Improved in vivo PET imaging of the adenosine A(2A) receptor in the brain using [(18)F]FLUDA, a deuterated radiotracer with high metabolic stability
PURPOSE: The adenosine A(2A) receptor has emerged as a therapeutic target for multiple diseases, and thus the non-invasive imaging of the expression or occupancy of the A(2A) receptor has potential to contribute to diagnosis and drug development. We aimed at the development of a metabolically stable...
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| Izdano u: | Eur J Nucl Med Mol Imaging |
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| Glavni autori: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8263428/ https://ncbi.nlm.nih.gov/pubmed/33532910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05164-4 |
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