PET Imaging of the Adenosine A(2A) Receptor in the Rotenone-Based Mouse Model of Parkinson’s Disease with [(18)F]FESCH Synthesized by a Simplified Two-Step One-Pot Radiolabeling Strategy

The adenosine A(2A) receptor (A(2A)R) is regarded as a particularly appropriate target for non-dopaminergic treatment of Parkinson’s disease (PD). An increased A(2A)R availability has been found in the human striatum at early stages of PD and in patients with PD and dyskinesias. The aim of this smal...

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Veröffentlicht in:Molecules
Hauptverfasser: Schröder, Susann, Lai, Thu Hang, Toussaint, Magali, Kranz, Mathias, Chovsepian, Alexandra, Shang, Qi, Dukić-Stefanović, Sladjana, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Wenzel, Barbara, Moldovan, Rareş-Petru, Pan-Montojo, Francisco, Brust, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180622/
https://ncbi.nlm.nih.gov/pubmed/32252340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071633
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