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PET Imaging of the Adenosine A(2A) Receptor in the Rotenone-Based Mouse Model of Parkinson’s Disease with [(18)F]FESCH Synthesized by a Simplified Two-Step One-Pot Radiolabeling Strategy

The adenosine A(2A) receptor (A(2A)R) is regarded as a particularly appropriate target for non-dopaminergic treatment of Parkinson’s disease (PD). An increased A(2A)R availability has been found in the human striatum at early stages of PD and in patients with PD and dyskinesias. The aim of this smal...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Schröder, Susann, Lai, Thu Hang, Toussaint, Magali, Kranz, Mathias, Chovsepian, Alexandra, Shang, Qi, Dukić-Stefanović, Sladjana, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Wenzel, Barbara, Moldovan, Rareş-Petru, Pan-Montojo, Francisco, Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180622/
https://ncbi.nlm.nih.gov/pubmed/32252340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071633
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