Synthesis, (18)F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography

Phosphodiesterase 2A (PDE2A) is highly and specifically expressed in particular brain regions that are affected by neurological disorders and in certain tumors. Development of a specific PDE2A radioligand would enable molecular imaging of the PDE2A protein via positron emission tomography (PET). Her...

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Publicado no:Molecules
Main Authors: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Egerland, Ute, Kranz, Mathias, Scheunemann, Matthias, Höfgen, Norbert, Steinbach, Jörg, Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272448/
https://ncbi.nlm.nih.gov/pubmed/26016549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20069591
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