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Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016

Cyclic nucleotide phosphodiesterases (PDEs) represent one of the key targets in the research field of intracellular signaling related to the second messenger molecules cyclic adenosine monophosphate (cAMP) and/or cyclic guanosine monophosphate (cGMP). Hence, non-invasive imaging of this enzyme class...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Schröder, Susann, Scheunemann, Matthias, Wenzel, Barbara, Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068090/
https://ncbi.nlm.nih.gov/pubmed/33917199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083832
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