Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012

Cyclic nucleotide phosphodiesterases (PDEs) are a class of intracellular enzymes that inactivate the secondary messenger molecules, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Thus, PDEs regulate the signaling cascades mediated by these cyclic nucleotides and aff...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Scheunemann, Matthias, Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273803/
https://ncbi.nlm.nih.gov/pubmed/27213312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21050650
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