Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016

Cyclic nucleotide phosphodiesterases (PDEs) represent one of the key targets in the research field of intracellular signaling related to the second messenger molecules cyclic adenosine monophosphate (cAMP) and/or cyclic guanosine monophosphate (cGMP). Hence, non-invasive imaging of this enzyme class...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Schröder, Susann, Scheunemann, Matthias, Wenzel, Barbara, Brust, Peter
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068090/
https://ncbi.nlm.nih.gov/pubmed/33917199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083832
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