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Design and Synthesis of a Series of Truncated Neplanocin Fleximers

In an effort to study the effects of flexibility on enzyme recognition and activity, we have developed several different series of flexible nucleoside analogues in which the purine base is split into its respective imidazole and pyrimidine components. The focus of this particular study was to synthe...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zimmermann, Sarah C., O’Neill, Elizaveta, Ebiloma, Godwin U., Wallace, Lynsey J. M., De Koning, Harry P., Seley-Radtke, Katherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270936/
https://ncbi.nlm.nih.gov/pubmed/25521119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191221200
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