Multi-target mode of action of a Clerodane-type diterpenoid from Polyalthia longifolia targeting African trypanosomes

Por Ebiloma, Godwin U., Katsoulis, Evangelos, Igoli, John O., Gray, Alexander I., De Koning, Harry P.
Publicado no Sci Rep (2018)

9-(2′-Deoxy-2′-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance

Por Ranjbarian, Farahnaz, Vodnala, Munender, Alzahrani, Khalid J. H., Ebiloma, Godwin U., de Koning, Harry P., Hofer, Anders
Publicado no Antimicrob Agents Chemother (2017)

The Strong Anti-Kinetoplastid Properties of Bee Propolis: Composition and Identification of the Active Agents and Their Biochemical Targets

Por Ebiloma, Godwin U., Ichoron, Nahandoo, Siheri, Weam, Watson, David G., Igoli, John O., De Koning, Harry P.
Publicado no Molecules (2020)

Sustainable Elimination (Zero Cases) of Sleeping Sickness: How Far Are We from Achieving This Goal?

Por Akazue, Pearl Ihuoma, Ebiloma, Godwin U., Ajibola, Olumide, Isaac, Clement, Onyekwelu, Kenechukwu, Ezeh, Charles O., Eze, Anthonius Anayochukwu
Publicado no Pathogens (2019)

A Review of the Antimalarial, Antitrypanosomal, and Antileishmanial Activities of Natural Compounds Isolated From Nigerian Flora

Por Ungogo, Marzuq A., Ebiloma, Godwin U., Ichoron, Nahandoo, Igoli, John O., de Koning, Harry P., Balogun, Emmanuel O.
Publicado no Front Chem (2020)

Design and Synthesis of a Series of Truncated Neplanocin Fleximers

Por Zimmermann, Sarah C., O’Neill, Elizaveta, Ebiloma, Godwin U., Wallace, Lynsey J. M., De Koning, Harry P., Seley-Radtke, Katherine L.
Publicado no Molecules (2014)

Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs

Por Nnadi, Charles O., Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi J., Lemgruber, Leandro, Schmidt, Thomas J., de Koning, Harry P.
Publicado no Molecules (2019)

European propolis is highly active against trypanosomatids including Crithidia fasciculata

Por Alotaibi, Abdullah, Ebiloma, Godwin U., Williams, Roderick, Alenezi, Samya, Donachie, Anne-Marie, Guillaume, Selome, Igoli, John O., Fearnley, James, de Koning, Harry P., Watson, David G.
Publicado no Sci Rep (2019)

Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

Por Rodenko, Boris, Wanner, Martin J., Alkhaldi, Abdulsalam A. M., Ebiloma, Godwin U., Barnes, Rebecca L., Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P.
Publicado no Antimicrob Agents Chemother (2015)

Functional and structural analysis of AT-specific minor groove binders that disrupt DNA–protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast

Por Millan, Cinthia R., Acosta-Reyes, Francisco J., Lagartera, Laura, Ebiloma, Godwin U., Lemgruber, Leandro, Nué Martínez, J. Jonathan, Saperas, Núria, Dardonville, Christophe, de Koning, Harry P., Campos, J. Lourdes
Publicado no Nucleic Acids Res (2017)

Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

Por Ajibaye, Olusola, Osuntoki, Akinniyi A., Balogun, Emmanuel O., Olukosi, Yetunde A., Iwalokun, Bamidele A., Oyebola, Kolapo M., Hikosaka, Kenji, Watanabe, Yoh-ichi, Ebiloma, Godwin U., Kita, Kiyoshi, Amambua-Ngwa, Alfred
Publicado no Malar J (2020)

The Chemical Characterization of Nigerian Propolis samples and Their Activity Against Trypanosoma brucei

Por Omar, Ruwida, Igoli, John O., Zhang, Tong, Gray, Alexander I., Ebiloma, Godwin U., Clements, Carol J., Fearnley, James, Edrada Ebel, RuAngeli, Paget, Tim, de Koning, Harry P., Watson, David G.
Publicado no Sci Rep (2017)

Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei...

Por Cerone, Michela, Uliassi, Elisa, Prati, Federica, Ebiloma, Godwin U., Lemgruber, Leandro, Bergamini, Christian, Watson, David G., de A. M. Ferreira, Thais, Roth Cardoso, Gabriella Simões Heyn, Soares Romeiro, Luiz A., de Koning, Harry P., Bolognesi, Maria Laura
Publicado no ChemMedChem (2019)

SAR of 4-Alkoxybenzoic Acid Inhibitors of the Trypanosome Alternative Oxidase

Por Meco-Navas, Alejandro, Ebiloma, Godwin U., Martín-Domínguez, Ana, Martínez-Benayas, Irene, Cueto-Díaz, Eduardo J., Alhejely, Amani Saud, Balogun, Emmanuel O., Saito, Machi, Matsui, Miho, Arai, Natsumi, Shiba, Tomoo, Harada, Shigeharu, de Koning, Harry P., Dardonville, Christophe
Publicado no ACS Med Chem Lett (2018)

Isolation of a Novel Flavanonol and an Alkylresorcinol with Highly Potent Anti-Trypanosomal Activity from Libyan Propolis

Por Siheri, Weam, Ebiloma, Godwin U., Igoli, John O., Gray, Alexander I., Biddau, Marco, Akrachalanont, Pilaslak, Alenezi, Samya, Alwashih, Mohammad A., Edrada-Ebel, RuAngelie, Muller, Sylke, Lawrence, Catherine E., Fearnley, James, Watson, David G., De Koning, Harry P.
Publicado no Molecules (2019)