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Carbocyclic 5′-nor “reverse” fleximers. Design, synthesis, and preliminary biological activity
A series of 5′-nor carbocyclic “reverse” flexible nucleosides or “fleximers” have been designed wherein the nucleobase scaffold resembles a “split” purine as well as a substituted pyrimidine. This modification was employed to explore recognition by both purine and pyrimidine metabolizing enzymes. Th...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849035/ https://ncbi.nlm.nih.gov/pubmed/24312722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1MD00094B |
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