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Hetero-expanded Purine Nucleosides. Design, Synthesis and Preliminary Biological Activity

Several thieno-expanded purine nucleoside analogues were synthesized for use as tools in ongoing investigations into nucleic acid structure and function in our laboratories. The inclusion of the thiophene ring system in the nucleoside endows the purine scaffold with advantages not previously availab...

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Detalhes bibliográficos
Main Authors: Seley-Radtke, Katherine L., Zhang, Zhibo, Wauchope, Orrette R., Zimmermann, Sarah C., Ivanov, Alexander, Korba, Brent
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785017/
https://ncbi.nlm.nih.gov/pubmed/18776540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn321
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