Tricyclic 2′-C-Modified Nucleosides as Potential Anti- HCV Therapeutics

[Image: see text] Promising biological activity in a number of therapeutic areas has been reported for both tricyclic nucleosides and 2′-modified nucleosides. In particular, di-substitution at the C-2′ position of nucleosides has resulted in significant activity against the Hepatitis C virus (HCV)....

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Main Authors: Wauchope, Orrette R., Tomney, Matthew J., Pepper, Joseph L., Korba, Brent E., Seley-Radtke, Katherine L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975515/
https://ncbi.nlm.nih.gov/pubmed/20845910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101482h
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