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Synthetic Routes to a Series of Proximal and Distal 2′-Deoxy Fleximers

Two series of innovative 2′-deoxy nucleoside analogues have been designed where the nucleobase has been split into its imidazole and pyrimidine subunits. This structural modification serves to introduce flexibility into the nucleobase scaffold while still retaining the elements required for recognit...

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Bibliographic Details
Main Authors: Wauchope, Orrette R., Velasquez, Melvin, Seley-Radtke, Katherine
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898542/
https://ncbi.nlm.nih.gov/pubmed/24465059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1316791
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