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Synthetic Routes to a Series of Proximal and Distal 2′-Deoxy Fleximers

Two series of innovative 2′-deoxy nucleoside analogues have been designed where the nucleobase has been split into its imidazole and pyrimidine subunits. This structural modification serves to introduce flexibility into the nucleobase scaffold while still retaining the elements required for recognit...

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Detalhes bibliográficos
Main Authors: Wauchope, Orrette R., Velasquez, Melvin, Seley-Radtke, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898542/
https://ncbi.nlm.nih.gov/pubmed/24465059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1316791
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