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Hetero-expanded Purine Nucleosides. Design, Synthesis and Preliminary Biological Activity

Several thieno-expanded purine nucleoside analogues were synthesized for use as tools in ongoing investigations into nucleic acid structure and function in our laboratories. The inclusion of the thiophene ring system in the nucleoside endows the purine scaffold with advantages not previously availab...

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Détails bibliographiques
Auteurs principaux: Seley-Radtke, Katherine L., Zhang, Zhibo, Wauchope, Orrette R., Zimmermann, Sarah C., Ivanov, Alexander, Korba, Brent
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785017/
https://ncbi.nlm.nih.gov/pubmed/18776540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn321
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