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Hetero-expanded Purine Nucleosides. Design, Synthesis and Preliminary Biological Activity

Several thieno-expanded purine nucleoside analogues were synthesized for use as tools in ongoing investigations into nucleic acid structure and function in our laboratories. The inclusion of the thiophene ring system in the nucleoside endows the purine scaffold with advantages not previously availab...

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Autores principales: Seley-Radtke, Katherine L., Zhang, Zhibo, Wauchope, Orrette R., Zimmermann, Sarah C., Ivanov, Alexander, Korba, Brent
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785017/
https://ncbi.nlm.nih.gov/pubmed/18776540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn321
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