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Hetero-expanded Purine Nucleosides. Design, Synthesis and Preliminary Biological Activity

Several thieno-expanded purine nucleoside analogues were synthesized for use as tools in ongoing investigations into nucleic acid structure and function in our laboratories. The inclusion of the thiophene ring system in the nucleoside endows the purine scaffold with advantages not previously availab...

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Autori principali: Seley-Radtke, Katherine L., Zhang, Zhibo, Wauchope, Orrette R., Zimmermann, Sarah C., Ivanov, Alexander, Korba, Brent
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785017/
https://ncbi.nlm.nih.gov/pubmed/18776540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn321
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