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A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens
Phosphoantigens stimulate Vγ9Vδ2 T cells after binding to BTN3A1 in target cells and cell-cell contact. We evaluated phosphoantigens including diphosphates, bisphosphonates, and prodrugs for ability to induce leukemia cells to stimulate Vγ9Vδ2 T cell interferon-γ secretion. Most compounds displayed...
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| 發表在: | Biochem Pharmacol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258176/ https://ncbi.nlm.nih.gov/pubmed/30391478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.10.035 |
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