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A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens

Phosphoantigens stimulate Vγ9Vδ2 T cells after binding to BTN3A1 in target cells and cell-cell contact. We evaluated phosphoantigens including diphosphates, bisphosphonates, and prodrugs for ability to induce leukemia cells to stimulate Vγ9Vδ2 T cell interferon-γ secretion. Most compounds displayed...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Hsiao, Chia-Hung Christine, Wiemer, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258176/
https://ncbi.nlm.nih.gov/pubmed/30391478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.10.035
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