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A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens
Phosphoantigens stimulate Vγ9Vδ2 T cells after binding to BTN3A1 in target cells and cell-cell contact. We evaluated phosphoantigens including diphosphates, bisphosphonates, and prodrugs for ability to induce leukemia cells to stimulate Vγ9Vδ2 T cell interferon-γ secretion. Most compounds displayed...
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| Publicat a: | Biochem Pharmacol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258176/ https://ncbi.nlm.nih.gov/pubmed/30391478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.10.035 |
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