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HMBPP analog prodrugs bypass energy-dependent uptake to promote efficient BTN3A1-mediated malignant cell lysis by Vγ9Vδ2 T lymphocyte effectors
Vγ9Vδ2 T effectors lyse cells in response to phosphorus-containing small molecules, providing primates a unique route to remove infected or malignant cells. Yet, the triggering mechanisms remain ill-defined. We examined lysis mediated by human Vγ9Vδ2 T effectors in response to the naturally-occurrin...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935553/ https://ncbi.nlm.nih.gov/pubmed/27271567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501833 |
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