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Specific requirements for Vγ9Vδ2 T cell stimulation by a natural adenylated phosphoantigen
Human Vγ9Vδ2 T lymphocytes recognize phosphorylated alkyl antigens. Isopentenyl pyrophosphate (IPP) was previously proposed as the main antigen responsible for Vγ9Vδ2 T cell activation by cancer cells. However ApppI, a metabolite in which the isopentenyl moiety is linked to ATP, was reported in cell...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Association of Immunologists
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809082/ https://ncbi.nlm.nih.gov/pubmed/19710470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901085 |
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