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Self-activation of Vγ9Vδ2 T cells by exogenous phosphoantigens involves TCR and butyrophilins

The high cytotoxic activity of Vγ9Vδ2 T lymphocytes against tumor cells makes them useful candidates in anticancer therapies. However, the molecular mechanism of their activation by phosphoantigens (PAgs) is not completely known. Many studies have depicted the mechanism of Vγ9Vδ2 T-cell activation b...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Laplagne, Chloé, Ligat, Laetitia, Foote, Juliet, Lopez, Frederic, Fournié, Jean-Jacques, Laurent, Camille, Valitutti, Salvatore, Poupot, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237548/
https://ncbi.nlm.nih.gov/pubmed/34183807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-021-00720-w
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