The intracellular B30.2 domain of Butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells

In humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections including Mycobacterium tuberculosis through recognition of small pyrophosphate containing organic molecules known as phosphoantigens (pAgs). Key to pAg-mediated activation of Vγ9Vδ2 T cells is the butyrophilin 3A1 (BTN3A1) protei...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sandstrom, Andrew, Peigné, Cassie-Marie, Léger, Alexandra, Crooks, James E., Konczak, Fabienne, Gesnel, Marie-Claude, Breathnach, Richard, Bonneville, Marc, Scotet, Emmanuel, Adams, Erin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028361/
https://ncbi.nlm.nih.gov/pubmed/24703779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.03.003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados