RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor

Human Vγ9Vδ2 T cells respond to tumour cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) through yet unknown mechanisms. Here, we developed an unb...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Sebestyen, Zsolt, Scheper, Wouter, Vyborova, Anna, Gu, Siyi, Rychnavska, Zuzana, Schiffler, Marleen, Cleven, Astrid, Chéneau, Coraline, van Noorden, Martje, Peigné, Cassie-Marie, Olive, Daniel, Lebbink, Robert Jan, Oostvogels, Rimke, Mutis, Tuna, Schuurhuis, Gerrit-Jan, Adams, Erin J, Scotet, Emmanuel, Kuball, Jürgen
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035041/
https://ncbi.nlm.nih.gov/pubmed/27210746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.081
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