RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor

Human Vγ9Vδ2 T cells respond to tumour cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) through yet unknown mechanisms. Here, we developed an unb...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Sebestyen, Zsolt, Scheper, Wouter, Vyborova, Anna, Gu, Siyi, Rychnavska, Zuzana, Schiffler, Marleen, Cleven, Astrid, Chéneau, Coraline, van Noorden, Martje, Peigné, Cassie-Marie, Olive, Daniel, Lebbink, Robert Jan, Oostvogels, Rimke, Mutis, Tuna, Schuurhuis, Gerrit-Jan, Adams, Erin J, Scotet, Emmanuel, Kuball, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035041/
https://ncbi.nlm.nih.gov/pubmed/27210746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.081
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker