RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor

Human Vγ9Vδ2 T cells respond to tumour cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) through yet unknown mechanisms. Here, we developed an unb...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Sebestyen, Zsolt, Scheper, Wouter, Vyborova, Anna, Gu, Siyi, Rychnavska, Zuzana, Schiffler, Marleen, Cleven, Astrid, Chéneau, Coraline, van Noorden, Martje, Peigné, Cassie-Marie, Olive, Daniel, Lebbink, Robert Jan, Oostvogels, Rimke, Mutis, Tuna, Schuurhuis, Gerrit-Jan, Adams, Erin J, Scotet, Emmanuel, Kuball, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035041/
https://ncbi.nlm.nih.gov/pubmed/27210746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.081
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